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Are loss-of-function variants relevant to complex disease?

Three members of the group (James, Luke & Jeff) were involved in a substantial undertaking (led by our colleague Daniel MacArthur) to study loss-of-function (LoF) variants in otherwise “normal”...

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1000 Genomes and Beyond: a retrospective

1000 Genomes and Beyond Conference held on 24-26 of June 2014 in Cambridge, UK was the latest of the 1000 Genome Project community meetings, marking the end of this grandiose endeavor launched in 2008....

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